366577646@qq.com
价格 | 2800.00 |
品牌 | Bioyears ![]() |
产地 | 美国 |
货号 | 10131 |
免疫原 | E. coli |
规格 | 25μl |
技术资料 | 查看技术资料 |
Rab4A Protein Q67L mutant [10131]
[25 µg]
Catalog Number: 10131 |
Product Name: Rab4A Protein Q67L mutant |
Synonyms: Member RAS oncogene family, RAB4, HRES-1/RAB4 |
Source: Human, recombinant full length, His6-tag |
Expression Host: E. coli |
Molecular Weight: 24 kDa |
Purity: >95% by SDS-PAGE |
Introduction: The Rab family of Ras-related GTP-binding protein Rab4 is involved in bidirectional sarcolemmal-vesicular Adrb2 trafficking, which occurs continuously in healthy hearts and is necessary for normal baseline adrenergic responsiveness and resensitization after catecholamine exposure. |
Amino Acid Sequence (1-213, Q67L) |
MSETYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGL ERFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVIILCGNKKDLDADREVTFL EASRFAQENELMFLETSALTGENVEEAFVQCARKILNKIESGELDPERMGSGIQYGDAALRQLRSPRRA QAPNAQECGC |
Properties |
Physical Appearance (form): Dissolved in 20mM Tris-HCl, pH8.0, 150mM NaCl. |
Physical Appearance (form): White or clear |
Concentration: 1 mg/mL |
Storage: -80°C |
Preparation Instructions: Centrifuge the vial before open the cap and reconstitute in water. Adding of 10 mM β-mercaptoethanol or 1 mM DTT into the solution to protect the protein is recommended and using of non-ionic detergents such as n-Dodecyl β-D-maltoside (DoDM) or polyethylene detergents (e.g. C12E10) also help to stabilize the protein. Avoid repeated freezing and thawing after reconstitution. The purity of His-tagged Rab4A Q67L was determined by SDS-PAGE and Coomassie Brilliant Blue Staining. |
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References: 1. Barbosa, M. D. F. S. et al., Genomics 30: 439-444, 1995. 2. Odley, A. et al., Proc. Nat. Acad. Sci. 101: 7082-7087, 2004. 3. Rousseau-Merck, M.-F. et al., Hum. Genet. 86: 350-354, 1991. 4. Zahraoui, A. et al., J. Biol. Chem. 264: 12394-12401, 1989. |
电话: 027-87561633
邮箱: Bioyears@126.com
电话: 027-87561633
邮箱: Bioyears@126.com
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