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Anti Ras Rabbit Polyclonal Antibody

价格2600.00
品牌Bioyears   
产地
货号21021
免疫原Rabbit
规格100μl
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  • 概述

    Ras [21021]
    [100 µL]


    Catalog Number:  21021
    Gene Symbol:  RAS
    Description:   Anti Ras Rabbit Polyclonal Antibody
    Background:   Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is facilitated by guanine nucleotide exchange factors (GEFs).
    Immunogen:   A synthetic peptide from the C-terminus of Ras
    Applications:   ELISA, WB, IHC
    Recommended Dilutions:   ELISA 1:100-1:5000
    WB 1:100-1:2000
    IHC 1:100-1:1000
    Concentration:   0.2 mg/ml
    Host:   Rabbit
    Format:   Liquid
    Clonality:   Polyclonal
    Isotype:   IgG
    Purity:   Purified from serum
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Ras antibody recognizes H-Ras, N-Ras and K-Ras from vertebrates.
    Storage Conditions:  Store at -20°C. Avoid freeze / thaw cycles

    Western blot:  
    HEK-293T whole-cell lysate was used for Western blot with anti Ras polyclonal antibody (cat # 21021).




    Publications:
    1.  DNA vaccine elicits an efficient antitumor response by targeting the mutant Kras in a transgenic mouse lung cancer model
        Gene Therapy 21, 888-896 (October 2014)




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