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Anti EGFR(E746-A750)del Mouse Monoclonal Antibody

价格4800
品牌Bioyears   
产地美国
货号26235
免疫原Mouse
规格100ul
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  • 概述

    EGFR(E746-A750)del [26235]
    [100ul]

    Catalog Number:  26235
    Gene Symbol:  EGFR/HER1/ERBB1
    Description:   Anti EGFR(E746-A750)del Mouse Monoclonal Antibody
    Background:   EGFR is a receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. It activates at least 4 major downstream signaling cascades including the RAS-RAF-MEK ERK, PI3 kinase AKT, PLCgamma PKC and STATs modules. Defects in EGFR are associated with lung cancer (LNCR).
    Immunogen:   A synthetic peptide from the internal region of EGFR which includes the deletion of E746-A750, human origin.
    Applications:   ELISA, WB
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:500-1:1000
    Concentration:   1 mg/ml
    Host:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Recognizes EGFR(E746-A750), but not wild type EGFR of vertebrates.
    Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles

    Western blot:  
    Western blot analysis of recombinant EGFR(E746-A750) and wildtype proteins. Purified His-tagged EGFR(E746-A750)del protein (aa 702-987) and wild-type protein (aa 702-987) were blotted with anti EGFR(E746-A750)del mouse antibody (Cat. #26235).



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