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Anti β catenin(A43V) Mouse Monoclonal Antibody

价格4800
品牌Bioyears   
产地美国
货号26170
免疫原Mouse
规格100ul
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  • 概述

    β catenin(A43V) [26170]
    [100 µL]


    Catalog Number:  26170
    Gene Symbol:  CTNNB1, CTNNB
    Description:   Anti β catenin(A43V) Mouse Monoclonal Antibody
    Background:   Beta-catenin(or β catenin) is a protein that in humans is encoded by the CTNNB1 gene. β catenin is a subunit of the cadherin protein complex and also acts as an intracellular signal transducer in the Wnt signaling pathway. Deregulation of beta-catenin signaling is an important event in the genesis of a number of malignancies, such as colon cancer, melanoma, hepatocellular carcinoma, ovarian cancer, endometrial cancer, medulloblastoma pilomatricomas, and prostate cancer.
    Immunogen:   A synthetic peptide from the internal region of β catenin which includes the mutation of A43V, human origin.
    Applications:   ELISA, WB, IF, IHC
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:500-1:2000 
    IHC: 1:50-1:100
    Concentration:   1 mg/ml
    Host:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:   Recognizes β catenin(A43V), but not wild type β catenin protein from vertebrates.
    Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles

    Western blot:  
    Western blot analysis of recombinant β catenin(A43V) and wildtype proteins. Purified His-tagged β catenin(A43V) protein (amino acids 1-76, lane 2) and corresponding wild type protein (lane 1) were blotted with anti β catenin(A43V) mouse monoclonal antibody (Cat. #26170).




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