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Anti ALK(R1275Q) Mouse Monoclonal Antibody

价格4800
品牌Bioyears   
产地美国
货号26151
免疫原Mouse
规格100ul
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  • 概述

    ALK(R1275Q) [26151]
    [100 µL]
    Catalog Number:  26151
    Gene Symbol:  ALK, CD246, NBLST3
    Description:   Anti ALK(R1275Q) Mouse Monoclonal Antibody
    Background:   Anaplastic lymphoma kinase (ALK) also known as CD246 (cluster of differentiation 246) is a tyrosine kinase receptor that plays an important role in the development of the brain and nervous systems. Deficiencies in ALK, which most commonly as a fusion with other genes, are indicated in cancers.
    Immunogen:   A synthetic peptide from the internal region of ALK which includes the mutation of R1275Q, human origin.
    Applications:   ELISA, WB, IHC
    Recommended Dilutions:   
    ELISA: 1:1000-1:5000 
    WB: 1:100-1:1000 
    IHC: 1:50-1:100
    Concentration:   0.5 mg/ml
    Host:   Mouse
    Format:   Liquid
    Clonality:   Monoclonal
    Isotype:   
    Purity:   Purified from ascites
    Storage buffer:
    Preservative:  no
    Constituents:  PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
    Species Reactivity:  Recognizes ALK(R1275Q), but not wild type ALK protein from vertebrates.
    Storage Conditions:   Store at -20°C. Avoid freeze / thaw cycles

    Western blot:  
    Western blot analysis of recombinant ALK(R1275Q) and wildtype proteins. Purified His-tagged ALK(R1275Q) protein (amino acids 1060-1620, lane 2) and corresponding wild type protein (lane 1) were blotted with Anti ALK(R1275Q) mouse monoclonal antibody (Cat. #26151).





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