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价格 | 2600.00 |
品牌 | NewEastBio ![]() |
产地 | 美国 |
货号 | 21020 |
免疫原 | Rabbit |
规格 | 100μl |
技术资料 | 查看技术资料 |
Gα13 [21020]
[100 µL]
Catalog Number: 21020 |
Gene Symbol: GNA13 |
Description: Anti Gα13 Rabbit Polyclonal Antibody |
Background: Heterotrimeric G proteins are essential cellular signal transducers. Gα13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Gα13 are being explored. |
Immunogen: A synthetic peptide from a unique region of Gα13 |
Applications: ELISA, WB, IHC |
Recommended Dilutions: ELISA: 1:100-1:5000 WB: 1:100-1:2000 IHC: 1:50-1:100 |
Concentration: 0.2 mg/ml |
Host: Rabbit |
Format: Liquid |
Clonality: Polyclonal |
Purity: Purified from serum |
Storage buffer: |
Preservative: no |
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol |
Species Reactivity: Gα13 polyclonal antibody recognizes Gα13 of vertebrates. |
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles |
Western blot: |
![]() | Western blot analysis of Gα13 proteins. Purified Gα13 protein was blot with anti Gα13 polyclonal antibody (Cat # 21020). |
Publications: |
1. Resistance to inhibitors of cholinesterase-8A (Ric-8A) is critical for growth factor receptor-induced actin cytoskeletal reorganization J Biol Chem. 2011 Sep 2;286(35):31055-61 |
2. Agonist activation of the G protein-coupled receptor GPR35 involves transmembrane domain III and is transduced via Galpha and beta-arrestin-2 Br J Pharmacol. 2011 Feb;162(3):733-48 |
3. Gα12/13 inhibition enhances the anti-cancer effect of bortezomib through PSMB5 downregulation Carcinogenesis (2010) |
4. Suppression of tumor angiogenesis by Galpha(13) haploinsufficiency J Biol Chem. 2009 Oct 2;284(40):27409-15 |
电话: 027-87561633
邮箱: Bioyears@126.com
电话: 027-87561633
邮箱: Bioyears@126.com
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